By Antonio Ciaccia, Co-Founder of 46brooklyn Research and President of 3 Axis Advisors As we close out 2025, it's time to examine what this year revealed about the prescription drug marketplace—and what it means for employers heading into 2026. I recently joined Scripta Insights for a "pharmacy benefits autopsy" to dissect the year's most significant developments. What emerged wasn't just a story about new drugs or evolving regulations, but rather a clear picture of how deepl

By Eric Levin, CEO, Scripta Insights   2026 is shaping up to be one of the most consequential years in pharmacy benefits in decades. Costs are accelerating. New channels are exploding. And GLP-1s are rewriting every budget model in HR and finance.   One of the biggest operational headaches will be something most plans are not prepared for:  helping members navigate the growing confusion caused by cash-pay and direct-to-consumer (DTC) drug programs.  With TrumpRx and others pr

The pharmacy and benefits landscape has become too complex for manual processes alone. Between high-velocity drug launches, opaque pricing models, shifting formularies, and unstructured regulatory data, teams navigating pharmacy decisions need stronger tools. Artificial intelligence, when used responsibly, can dramatically improve the speed, accuracy, and consistency of Rx Navigation workflows. But like any powerful technology, it comes with guardrails. Below are the key do’s

The pharmacy benefits landscape is shifting faster than ever. Between policy changes, new market dynamics, and breakthrough medications, benefits leaders are navigating unprecedented complexity. Here are the top questions we're hearing from plan sponsors – and the answers you need now. Q: How will TrumpRx affect our pharmacy costs and benefit design?   A:  TrumpRx could reshape the prescription drug landscape in three significant ways. First, by tying U.S. drug prices to inte

Mark Cuban always tells it straight – and he certainly did that during our recent fireside chat with CEO Eric Levin.   He cut straight to the chase: the chaos in pharmacy benefits is not accidental, but self-insured employers have more power than they think. By making the right moves, plan sponsors can change the status quo and drive serious Rx savings.   Here are the five most actionable steps to act on today.   1. Ask for Cash Pay Purchases to Count Toward Deductibles   For

Let's cut through the noise. Benefits professionals are busy, pharmacy is complicated, and you need straight answers to strategic questions. Not fluff. Not jargon. Just clear information about how member engagement works, how solutions integrate, and what ROI actually looks like. Below are the most important questions we're hearing from benefits pros like you — and the direct answers that help you evaluate what's right for your organization.   Q: Can Scripta work with a trans